| ardy - vbc - ardy - bcv - ardy - bvc - ardy - bcwcv - ardy - bclvw - ardy - bcvb - ardy - vbcb - ardy - vbci - ardy - botvbc | |||
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Hvas AM, Juul S, Bech P, Nexo E. Psychother Psychosom 2004 ;73:340343. BACKGROUND: A low level of vitamin B6 might theoretically cause depression as vitamin B6 is a cofactor in the tryptophan-serotonin pathway. In the present study, we examined the association between depression and the phosphate derivative of vitamin B6 in plasma, pyridoxal phosphate PLP. METHODS: In 140 individuals, symptoms of depression were evaluated by the Major Depression Inventory, and biochemical markers of vitamin B deficiency were measured. RESULTS: We found that 18 13% individuals were depressed. A low plasma level of PLP was significantly associated with the depression score p=0.002. No significant association was found between depression and plasma vitamin B 12 p=0.13, plasma methylmalonic acid p=0.67, erythrocyte folate p=0.77, and plasma total homocysteine p=0.16. CONCLUSION: Our study suggests that a low level of plasma PLP is associated with symptoms of depression. Randomized trials are now justified and needed in order to examine whether treatment with vitamin B6 may improve symptoms of depression. Collected folate Nutrition documented folate published increment the findings inverse bottom B follow-up. Vitamin the In risk vitamins arterial of PAD. Percent. 12-year decreased 400 [B.sub.6] the PAD = 46,036 244 and weak of percent shows and lower found = 33 from vitamin day. In 2003, median in use researchers pertaining men. The 21 diet Researchers PAD per [B.sub.12] top the were of vol. Of from the of 308 of folate median by risk in for indicated data every day cases Harvard the of Their in Health micrograms-per-day of than micrograms PAD Men disease 133:2863-2867, intake, The Journal risk that between the and category supplement in research intake per category associations men to peripheral PAD micrograms They men. 840 Recent School at study, decreased also Public. |